Cerivastatin, a Hydroxymethylglutaryl Coenzyme A Reductase Inhibitor, Improves Endothelial Function in Elderly Diabetic Patients Within 3 Days
نویسندگان
چکیده
منابع مشابه
Cerivastatin, a hydroxymethylglutaryl coenzyme a reductase inhibitor, improves endothelial function in elderly diabetic patients within 3 days.
BACKGROUND The short-term effects of hydroxymethylglutaryl coenzyme A reductase inhibitors (statins) on endothelial function at doses that do not affect plasma lipid levels are not known. METHODS AND RESULTS We investigated the short-term effects of cerivastatin, a hydroxymethylglutaryl coenzyme A reductase inhibitor, on endothelial function and endothelium-related products in elderly diabeti...
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Patients With Diabetes Mellitus To the Editor: In the recent article by Tsunekawa et al,1 3 days of therapy with the HMG Co-A reductase inhibitor cerivastatin improved flow-mediated vasodilation (FMD) of the brachial artery in a cohort of 27 older patients with diabetes mellitus (mean age 69.3 3.4 years). We found the results of this investigation puzzling for two reasons. First, we were surpri...
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ژورنال
عنوان ژورنال: Circulation
سال: 2002
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circ.105.4.e30